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Energy & fatigue

Mitochondrial output and recovery — the newest, earliest-stage biology.

MOTS-c · creatine · CoQ10

Our writeups

0

Graded dossiers for energy & fatigue are in production. The primary papers and regulatory reads are below now — our writeups land on top as they publish.

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Primary papers

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MOTS-c, a mitochondrial-derived peptide, promotes metabolic homeostasis
Lee C, et al. Cell Metabolism 2015;21(3):443–454
Doesn't show: Cell/animal models; human clinical efficacy and long-term safety not established.
Mechanistic↗

Regulatory

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FDA Pharmacy Compounding Advisory Committee — 7-peptide review
FDA · docket FDA-2025-N-6895 · 23–24 Jul 2026
Advisory vote on the 503A compounding list — not approval, not consumer legalisation.
official↗

Educational purpose only. PEPHORMIA aggregates and grades published scientific literature. Nothing here is medical advice, diagnosis, or treatment, and nothing here is a recommendation to obtain, dose, or use any compound. We do not sell, supply, or facilitate access to prescription medicines or injectable peptides. Products offered are cosmetic-grade topical formulations described by appearance only. Peptide and hormone use carries real risks — consult a qualified healthcare professional before any decision. Statements have not been evaluated by the TGA or FDA.